Many USB 3.0 cables and devices don’t have adequate shielding, and this causes radio frequency leakage that can interfere with Bluetooth wireless. Symptoms include Bluetooth keyboards/mice that lose connectivity, and choppy audio from Bluetooth earphones/speakers. Workarounds include moving USB devices always from Bluetooth devices, or buying better shielded USB 3.0 cables. This issue in prevalent enough on the Mac side that Apple has published the following support article on the subject: https://support.apple.com/en-us/HT203729